Women’s Health Research Institute

The Women’s Health Research Institute is a university unit aimed at conducting scientific activities in the field of medicine and health sciences, focusing on the health needs of women.

The scientific activities of the Institute primarily focus on research related to reproductive health, with particular emphasis on the diagnosis and treatment of infertility and endometriosis. Within our scientific projects, we develop new diagnostic strategies to improve the quality of life for women dealing with these conditions.

The main objective of our scientific research is to utilize new large-scale “omics” technologies in the development of an early, non-invasive diagnostic method for endometriosis. To achieve this goal, the Institute conducts scientific projects in the fields of proteomics, glycomics and metabolomics, as well as analyzes the obtained data. These projects are carried out in collaboration with other scientific centers in Poland and worldwide, using funds, including grants, provided by national institutions. An additional element of the Institute’s activities is conducting research on the epidemiology of female cancers.

Prof. Dr hab. med. Piotr Laudański

In his professional work, he is interested in various aspects of obstetrics, gynecology, and reproductive medicine, with particular emphasis on the care of patients with endometriosis, infertile couples due to various reasons, and pregnancies after infertility treatment. In addition to his basic specialization in obstetrics and gynecology, he has also obtained subspecializations in perinatology and gynecological endocrinology and reproductive medicine. He was awarded the title of professor in 2016. A member of international scientific societies, including the Polish Society of Gynecologists and Obstetricians, the European Society of Human Reproduction and Embryology, and the Polish Society of Reproductive Medicine and Embryology. He is the author of numerous scientific publications, patents, and a scientific editor of books including “Infertility: Common Problems,” the second part of the series “Infertility – Latest Recommendations,” and “Gynecological Endocrinology and Infertility”. He regularly lectures at national and international conferences and conducts courses for gynecologists on infertility and gynecological endocrinology.

Dr hab. n. med. Cezary Wojtyła

Dr Cezary Wojtyła is a graduate of the Medical University of Warsaw. In 2016, he obtained a doctorate in medical sciences, and in 2023, he obtained a habilitation degree in medical sciences and health sciences. In 2020, he obtained a specialist title in obstetrics and gynecology. In his professional and scientific work, he is particularly involved in the diagnosis and treatment of endometriosis and infertility. He has conducted several scientific projects aimed at identifying new biomarkers of endometriosis, including the grant from the National Science Centre: “The use of neoglycolipid technology-based microarrays in multiomic research on the biomarker of endometriosis”. This project was carried out in collaboration with Imperial College in London. In 2022, he received reward from the Minister of Science and Higher Education for outstanding young scientists.

  1. “The use of neoglycolipid technology-based microarrays in multiomic research on the biomarker of endometriosis “.
  2. “Targeted proteomic analysis of serum and peritoneal fluid from women with endometriosis”.
  3. “Metabolomic analysis of serum and peritoneal fluid from women with endometriosis”.
  4. “Creation and validation of a protein panel facilitating the diagnosis of endometriosis based on the examination of peritoneal fluid and serum”.
  5. “Determination of the diagnostic potential of the protein panel developed for endometriosis diagnosis”.
  1. Laudański P, Rogalska G, Warzecha D, Lipa M, Mańka G, Kiecka M, Spaczyński R, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Neuman T, Adler P, Peterson H, Salumets A, Wielgos M. Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis. Hum Reprod. 2023 Apr 3;38(4):629-643. doi: 10.1093/humrep/dead011.
    Impact Factor: 6.1; MEiN: 140
  2. Wasilewska A, Grabowska M, Moskalik-Kierat D, Brzoza M, Laudański P, Garley M. Immunological Aspects of Infertility-The Role of KIR Receptors and HLA-C Antigen. Cells. 2023 Dec 27;13(1):59. doi: 10.3390/cells13010059.
    Impact Factor: 6.0; MEiN: 140
  3. Oldak L, Lukaszewski Z, Leśniewska A, Goławski K, Laudański P, Gorodkiewicz E. Development of an SPRi Test for the Quantitative Detection of Cadherin 12 in Human Plasma and Peritoneal Fluid. Int J Mol Sci. 2023 Nov 29;24(23):16894. doi: 10.3390/ijms242316894.
    Impact Factor: 5.6; MEiN: 140
  4. Meltsov A, Saare M, Teder H, Paluoja P, Arffman RK, Piltonen T, Laudanski P, Wielgoś M, Gianaroli L, Koel M, Peters M, Salumets A, Krjutškov K, Palta P. Targeted gene expression profiling for accurate endometrial receptivity testing. Sci Rep. 2023 Aug 26;13(1):13959. doi: 10.1038/s41598-023-40991-z.
    Impact Factor: 4.6; MEiN: 140
  5. Lisowska-Myjak B, Skarżyńska E, Wróbel M, Mańka G, Kiecka M, Lipa M, Warzecha D, Spaczyński R, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Wielgoś M, Laudański P. Investigation of the Changes in Concentrations of Vitamin D-Binding Protein and Lactoferin in Plasma and Peritoneal Fluid of Patients with Endometriosis. Int J Mol Sci. 2023 Apr 25;24(9):7828. doi: 10.3390/ijms24097828.
    Impact Factor: 5.6; MEiN: 140
  6. Urban A, Warzecha D, Laudanski P, Pietrzak B, Wielgos M. Personalized embryo transfer (pET) guided by endometrial receptivity (ER) assessment – a possibility to increase effectiveness of IVF procedures. Review of available methods. Ginekol Pol. 2023;94(12):1004-1010. doi: 10.5603/GP.a2023.0041.
    Impact Factor: 1.3; MEiN: 40
  7. Omeljaniuk WJ, Laudański P, Miltyk W. The role of miRNA molecules in the miscarriage process. Biol Reprod. 2023 Jul 11;109(1):29-44. doi: 10.1093/biolre/ioad047.
    Impact Factor: 3.6; MEiN: 200
  8. Zielinska Z, Oldak L, Kacperczyk-Bartnik J, Koc-Żórawska E, Żórawski M, Laudanski P, Gorodkiewicz E. An Array SPRi Biosensor for the Determination on PARP-1 in Blood Plasma. Biomedicines. 2023 Feb 17;11(2):602. doi: 10.3390/biomedicines11020602.
    Impact Factor: 4.7; MEiN: 100
  9. Skarżyńska E, Wróbel M, Zborowska H, Kołek MF, Mańka G, Kiecka M, Lipa M, Warzecha D, Spaczyński R, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Wielgoś M, Lisowska-Myjak B, Laudański P. The Influence of Lactoferrin in Plasma and Peritoneal Fluid on Iron Metabolism in Women with Endometriosis. Int J Mol Sci. 2023 Jan 13;24(2):1619. doi: 10.3390/ijms24021619.
    Impact Factor: 5.6; MEiN: 140
  10. Warzecha D, Załęcka J, Mańka G, Kiecka M, Lipa M, Spaczyński R, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Wielgoś M, Ołdak Ł, Leśniewska A, Gorodkiewicz E, Laudański P. Plasma and Peritoneal Fluid Fibronectin and Collagen IV Levels as Potential Biomarkers of Endometriosis. Int J Mol Sci. 2022 Dec 10;23(24):15669. doi: 10.3390/ijms232415669.
    Impact Factor: 5.6; MEiN: 140
  11. Goławski Ksawery, Giermaziak Wojciech, Ciebiera Michał, Wojtyła Cezary. Excessive Gestational Weight Gain and Pregnancy Outcomes. Journal of Clinical Medicine. 2023, 12(9), 3211; https://doi.org/10.3390/jcm12093211
    Impact Factor: 3.9; MEiN: 140
  12. Lidia Korczynska, Natalia Zeber-Lubecka, Magdalena Zgliczynska, Elzbieta Zarychta, Kornelia Zareba, Cezary Wojtyla, Michalina Dabrowska, Michal Ciebiera. The role of microbiota in the pathophysiology of uterine fibroids – a systematic review (2023.) The role of microbiota in the pathophysiology of uterine fibroids – a systematic review. Frontiers in Cellular and Infection Microbiology. 13:1177366. doi: 10.3389/fcimb.2023.1177366
    Impact Factor: 5.7; MEiN: 100
  13. Wróbel M, Zuzanna Z, Ołdak Ł, Kalicka A, Mańka G, Kiecka M, Spaczyński RZ, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluz T, Kluza M, Pierzyński P, Wojtyła Cezary, Lipa M, Warzecha D, Wielgoś M, Sawicki W, Gorodkiewicz E, Laudański P. Evaluation of Proteasome and Immunoproteasome Levels in Plasma and Peritoneal Fluid in Patients with Endometriosis. International Journal of Molecular Sciences. 2023 Sep 21;24(18):14363. doi: 10.3390/ijms241814363.
    Impact Factor: 5.6; MEiN: 140
  14. Wojtyła Cezary, Bertuccio P, Giermaziak W, Santucci C, Odone A, Ciebiera M, Negri E, Wojtyła A, La Vecchia C. European trends in ovarian cancer mortality, 1990-2020 and predictions to 2025. European Journal of Cancer. 2023 Sep 26;194:113350. doi: 10.1016/j.ejca.2023.113350.
    Impact Factor: 8.4; MEiN: 140
  15. Michal Zygarowicz, Joanna Kacperczyk-Bartnik, Janusz Sierdzinski, Cezary Wojtyla, Piotr Pierzynski, Grzegorz Manka, Mariusz Kiecka, Robert Z Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Michal Lipa, Damian Warzecha, Miroslaw Wielgos, Ewa Koc-Zorawska, Marcin Zorawski, Piotr Laudanski. Plasma and Peritoneal Fluid Annexin A2 Levels in Patients with Endometriosis. Journal of Inflammation Research. 2023:16 5959–5969. doi: https://doi.org/10.2147/JIR.S421389
    Impact Factor: 4.5; MEiN: 140
  16. Wojtyla Cezary, Tołwiński Ignacy, Laudański Piotr. The Use of the Neoglycolipid-Based Oligosaccharide Microarray System in the Diagnosis of Endometriosis – Preliminary Study. Journal of Inflammation Research. 2024; 17: 899 – 908 https://doi.org/10.2147/JIR.S439709
    Impact Factor: 4.5; MEiN: 140
  17. Zyguła A, Sankiewicz A, Sakowicz A, Dobrzyńska E, Dakowicz A, Mańka G, Kiecka M, Spaczynski R, Piekarski P, Banaszewska B, Jakimiuk A, Issat T, Rokita W, Młodawski J, Szubert M, Sieroszewski P, Raba G, Szczupak K, Kluza T, Kluza M, Pierzyński P, Wojtyla Cezary, Lipa M, Warzecha D, Wielgos M, Cendrowski K, Gorodkiewicz E, Laudanski P. Is the leptin/BMI ratio a reliable biomarker for endometriosis? Frontiers in Endocrinology (Lausanne). 2024;15:1359182. doi: 10.3389/fendo.2024.1359182.
    Impact Factor: 5.2; MEiN: 100